Product Description

MCP-1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11650-50, RA11650-100

Citations, Manuals and MSDS Available upon request.

Background: C-C motif chemokine ligand 2 (CCL2) Homo sapiens This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013],

Condition: Purified antibody in PBS containing 0.03% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 6347

SWISS: P13500

Source: Mouse

Research Use Only