Product Description

MCP-1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11650-50, RA11650-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: C-C motif chemokine ligand 2 (CCL2) Homo sapiens This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013],

Reactivity: Human

Host: Mouse

Applications: WB, ELISA

Alternate Names: CCL2, MCP1, SCYA2, C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2

Clonality: Monoclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Purified antibody in PBS containing 0.03% sodium azide.

Human Gene ID: 6347

Research Use Only