Reed Bio
MCP Polyclonal Antibody - RA33266
MCP Polyclonal Antibody - RA33266
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MCP Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA33266-50, RA33266-100
Citations, Manuals and MSDS Available upon request.
Background: CD46 molecule (CD46) Homo sapiens The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010],
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 4179
Protein MW (KDa): 43
SWISS: P15529
Source: Rabbit
Research Use Only
