MDH1 Polyclonal Antibody
Catalogue Numbers: BS60457-50, BS60457-100
Sizes: 50µl, 100µl
Alternative Name: Malate dehydrogenase, cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; MDHA; MDHC; cMDH
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P40925
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh). MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MDH1 polyclonal antibody detects endogenous levels of MDH1 protein.
Bioworld Molecular Weight: ~ 36 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of MDH1 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: PC12 cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human MDH1.
Conjugate: Unconjugated
Modification: Unmodified