Product Description

MDR3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33272-50, RA33272-100

Citations, Manuals and MSDS Available upon request.

Background: ATP binding cassette subfamily B member 4 (ABCB4) Homo sapiens The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5244

Protein MW (KDa): 141

SWISS: P21439

Source: Rabbit

Research Use Only