Reed Bio
MDSP Rabbit Polyclonal Antibody - RA27120
MDSP Rabbit Polyclonal Antibody - RA27120
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MDSP Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA27120-50, RA27120-100
Citations, Manuals and MSDS Available upon request.
Background: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000
Applications: WB
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 51207
SWISS: Q6B8I1
Source: Rabbit
Research Use Only
