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MDSP Rabbit Polyclonal Antibody - RA27120

MDSP Rabbit Polyclonal Antibody - RA27120

Regular price $336.00 CAD
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MDSP Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27120-50, RA27120-100

Citations, Manuals and MSDS Available upon request.

Background: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 51207

SWISS: Q6B8I1

Source: Rabbit

Research Use Only

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