Product Description

ME3 (R576) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3339-50, BS3339-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ME3 (malic enzyme 3), also known as NADP-ME (NADP-dependent malic enzyme, mitochondrial), is a 604 amino acid protein of the mitochondrial matrix that catalyzes the conversion of (S)-malate and NADP+ to pyruvate, carbon dioxide and NADPH. A member of the malic enzymes family, ME3 utilizes manganese and magnesium as cofactors and is expressed in tissues that divide at a low rate. The gene encoding ME3 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: NADP-dependent malic enzyme, mitochondrial, NADP-ME, Malic enzyme 3, ME3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 547-598 of Human ME3.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ME3 (R576) polyclonal antibody detects endogenous levels of ME3 protein.

Molecular Weight: ~ 67 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16798

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only