MeCP2 Rabbit pAb - EA020

MeCP2 Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: EA020-50, EA020-100

Citations, Manuals and MSDS Available upon request.

Background: Methyl-CpG-binding protein 2 (MeCP2), whose exact function is unclear. It appears to help regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though this protein is found throughout the body.Within the brain, the MeCP2 protein is important for the function of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the genes that are known to be regulated by the MeCP2 protein play a role in normal brain function, particularly the maintenance of synapses.

Alternate Name: Methyl CpG Binding Protein 2 ; RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation, X-linked 16

Source: Rabbit

Applications: WB

Dilution: WB 1:2, 000

Reactivity: Human

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Polyclonal

Isotype: IgG

Concentration: 1mg/mL

Observed Band (KD): 53kDa

Human Gene ID: 4204

Human SWISS Prot NO: P51608

Subcellular Location: Nucleus

Research Use Only