Product Description

MED18 (V102) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3141-50, BS3141-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In mammalian cells, transcription is regμlated in part by high molecμlar weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such mμlti-protein structure that functions as a bridge between regμlatory proteins and Pol II, thereby regμlating Pol II-dependent transcription. Med18 (mediator complex subunit 18), also known asp28b, is a 208 amino acid protein that localizes to nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med18 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18, p28b, MED18

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 72-120 of Human MED18.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MED18 (V102) polyclonal antibody detects endogenous levels of MED18 protein.

Molecular Weight: ~ 24 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BUE0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only