MEF2A Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90835-50, BS90835-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q02078(Human) Q60929(Mouse) Q2MJT0(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Background: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: MEF2A polyclonal antibody detects endogenous levels of MEF2A protein.
Bioworld Molecular Weight: 54 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of MEF2A on rat spleen tissue lysate using anti-MEF2A antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Alternative Name: MEF2A, MEF2, ADCAD1, MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A), MEF2, MEF2A, MEF2A, Myocyte enhancer factor 2A, Myocyte-specific enhancer factor 2A, RSRFC4, RSRFC9, Serum response factor like protein 1, Serum response factor-like protein 1,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified