Product Description

MEK-5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27173-50, RA27173-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase kinase 5 (MAP2K5) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:1000-2000 IHC: 1:200-500

Alternative Names: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5067

Protein MW (KDa): 49

SWISS: Q13163

Source: Rabbit

Research Use Only