MEK-5 rabbit pAb - ES20665

MEK-5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20665-50, ES20665-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],

Alternate Name: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5

Source: Rabbit

Applications: WB; IHC; IF

Dilution: WB: 1:1000-2000 IHC: 1:200-500

Reactivity: Human; Mouse; Rat

Immunogen: Recombinant Protein of MEK-5

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 49kD

Human Gene ID: 5067

Human SWISS Prot NO: Q13163

Subcellular Location: nucleus, cytoplasm, spindle, cytosol,

Research Use Only