Product Description

MEKK2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11207-50, MB11207-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y2U5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates the kinases involved in the MAP kinase signaling pathway including MAPK7 and MAP2K4. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases (IKKs), and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2 (PRKCL2/PRK2), which suggests its involvement in PRKCL2 regulated signaling process.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 70 kDa; Observed MW: 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MEKK2 in C6, 3T3, Hela lysates using MEKK2 antibody., Immunocytochemistry analysis of MEKK2 in Hela using MEKK2 antibody, and DAPI

Alternative Name: MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein kinase kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2

Immunogen: A synthetic peptide of human MEKK2

Conjugate: Unconjugated

Modification: Unmodified