MEL-1A-R Polyclonal Antibody - BT-AP05360

MEL-1A-R Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05360-20, BT-AP05360-50, BT-AP05360-100

Citations, Manuals and MSDS Available upon request.

Background: MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Research Areas: Neuroscience

Target Protein: MTNR1A

Applications: IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MEL-1A-R Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 39375

UniProt Accession: Human: P48039; Mouse: Q61184; Rat: P49218

Synonyms: MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

GeneID: Human: 4543; Mouse: 17773

Research Use Only