Product Description

MEL-1A-R Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27180-50, RA27180-100

Citations, Manuals and MSDS Available upon request.

Background: melatonin receptor 1A (MTNR1A) Homo sapiens This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Applications: IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4543

SWISS: P48039

Source: Rabbit

Research Use Only