MEL-1A-R rabbit pAb - ES6287

MEL-1A-R rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6287-50, ES6287-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008],

Alternate Name: MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MTR1A. AA range:191-240

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4543

Human SWISS Prot NO: P48039

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only