MELK rabbit pAb - ES8105

MELK rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8105-50, ES8105-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis., PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily., similarity:Contains 1 KA1 (kinase-associated) domain., similarity:Contains 1 protein kinase domain., subunit:Interacts with ZNF622 and PPP1R8., tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,

Alternate Name: MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human MELK. AA range:431-480

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 75kD

Human Gene ID: 9833

Human SWISS Prot NO: Q14680

Subcellular Location: Cell membrane; Peripheral membrane protein.

Research Use Only