Menin Monoclonal Antibody-MB10297

Menin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10297-50, MB10297-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O00255

Host: Rabbit

Reactivity: Human, Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Menin in K562, C6Lysates using Menin antibody.

Bioworld Molecular Weight: Calculated MW: 68 kDa; Observed MW: 68 kDa

Specificity: IgG

Alternative Name: MEN1; SCG2; Menin

Immunogen: A synthetic peptide of human Menin

Conjugate: Unconjugated

Modification: Unmodified