Product Description

MEP1B Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33289-50, RA33289-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: meprin A subunit beta (MEP1B) Homo sapiens Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 77

Protein Molecular Weight (kDa): 77

Storage: -20°C/1 year

Human Gene ID: 4225

Human SwissProt Number: Q16820

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only