MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb - ES8458

MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8458-50, ES8458-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],

Alternate Name: MERTK MER

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 110kD

Human Gene ID: 10461/7301

Human SWISS Prot NO: Q12866/Q06418

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only