MERTK Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5443-20, A5443-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 110kDa
Observed Molecular Weight: 150-200kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 10461
SWISS: Q12866
Alternate Names: MER; RP38; c-Eyk; c-mer; Tyro12; MERTK
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Neuroscience.
NCBI Alias: MERTK
Research Use Only