Product Description

MESP2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60610-50, BS60610-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MESP2 (mesoderm posterior 2 homolog), also known as SCDO2 or bHLHc6 (class C basic helix-loop-helix protein 6), is a 397 amino acid protein that contains one basic helix-loop-helix (bHLH) domain, a motif that mediates protein dimerization and can bind to the E-box sequence of DNA. Localized to the nucleus, MESP2 functions as a transcription factor that, via its bHLH domain, participates in the epithelialization and the development of the cardiac and somitic mesoderm. MESP2 is involved in somitogenesis and Notch pathways and is encoded by a gene that maps to human chromosome 15q26.1. Defects in the MESP2 gene are the cause of an autosomal recessive disorder known as spondylocostal dysostosis type 2 (SCDO2).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Mesoderm posterior protein 2, Class C basic helix-loop-helix protein 6, bHLHc6, MESP2, BHLHC6, SCDO2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human MESP2

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MESP2 polyclonal antibody detects endogenous levels of MESP2 protein.

Molecular Weight: ~ 42 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q0VG99

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only