Product Description

Met Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30798-50, RA30798-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MET proto-oncogene, receptor tyrosine kinase (MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section)

Alternate Names: MET, YM3679

Clonality: Polyclonal

Dilution: IHC 1:100-200

Molecular Weight: 140170

Protein Molecular Weight (kDa): 140170

Storage: -20°C/1 year

Human Gene ID: 4233

Human SwissProt Number: P08581

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only