MFN1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-10454-60, E-AB-10454-120, E-AB-10454-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MFN1
Target Synonym: Fzo homolog; Hfzo1; Hfzo2; MFN 1; Mfn1; MFN1; Mitochondrial transmembrane GTPase Fzo 1; Mitochondrial transmembrane GTPase FZO 2; Mitochondrial transmembrane GTPase FZO1B; Mitofusin 1; Mitofusin-1; Mitofusin1; MS996; Putative transmembrane GTPase; Transmembrane GTPase MFN1
Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8IWA4
Background: The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human MFN1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only