Product Description

Mfn2 (F403) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3682-50, BS3682-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MFN2 is an essential transmembrane GTPase which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton, plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. It plays an important role in the regμlation of vascμlar smooth muscle cell proliferation. Defects in MFN2 lead to Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Mitofusin-2, Transmembrane GTPase MFN2, CPRP1, KIAA0214, MFN2,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 381-430 of Human Mfn2.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Mfn2 (F403) polyclonal antibody detects endogenous levels of Mfn2 protein.

Molecular Weight: ~ 86 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95140

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only