Product Description

Mfn2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21349-50, RA21349-100

Citations, Manuals and MSDS Available upon request.

Background: mitofusin 2 (MFN2) Homo sapiens This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Alternative Names: MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 9927

Protein MW (KDa): 86

SWISS: O95140

Source: Rabbit

Research Use Only