mGluR-6 (A865) Polyclonal Antibody-BS1146

mGluR-6 (A865) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1146-50, BS1146-100

Sizes: 50µl, 100µl

Swiss-Prot: O15303

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: mGluR6 (A865) polyclonal antibody detects endogenous levels of mGluR6 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of mGluR-6 (A865) polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: NIH-3T3 cell lysate
Lane 3: Raw264.7 cell lysate
Lane 4: H9C2 cell lysate, Immunohistochemistry (IHC) analyzes of mGluR-6 (A865) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 100 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6

Immunogen: Synthetic peptide, corresponding to amino acids 841-890 of Human mGluR-6.

Conjugate: Unconjugated

Modification: Unmodified