mGluR5 rabbit pAb - ES2786

mGluR5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2786-50, ES2786-100

Citations, Manuals and MSDS Available upon request.

Background: glutamate metabotropic receptor 5 (GRM5) Homo sapiens This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

Alternate Name: GRM5; GPRC1E; MGLUR5; Metabotropic glutamate receptor 5; mGluR5

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human GRM5. AA range:21-70

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 130kD

Human Gene ID: 2915

Human SWISS Prot NO: P41594

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only