Product Description

Mi2-α Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11665-50, RA11665-100

Citations, Manuals and MSDS Available upon request.

Background: chromodomain helicase DNA binding protein 3 (CHD3) Homo sapiens This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; FCM

Species Cross-Reactivity: Human; Mouse; Rat; Bovine; Dog; Pig

GeneID (Human): 1107

SWISS: Q12873

Source: Mouse

Research Use Only