Mi2-β rabbit pAb - ES4590

Mi2-β rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4590-50, ES4590-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

Alternate Name: CHD4; Chromodomain-helicase-DNA-binding protein 4; CHD-4; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1108

Human SWISS Prot NO: Q14839

Subcellular Location: Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Associates with centrosomes in interphase.

Research Use Only