Product Description

MICU1 Monoclonal Antibody (Mix)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0061-20, BT-MCA0061-50, BT-MCA0061-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Areas: Immunology; Signal Transduction; Metabolism

Target Protein: MICU1

Applications: WB, IF, ICC, IHC-p

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Calcium uptake protein 1, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9BPX6; Mouse: Q8VCX5; Rat: Q6P6Q9

Synonyms: Calcium uptake protein 1; mitochondrial; Atopy-related autoantigen CALC; ara CALC; Calcium-binding atopy-related autoantigen 1; allergen Hom s 4

GeneID: Human: 10367

Research Use Only