MIDN Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12568-60, E-AB-12568-120, E-AB-12568-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MIDN
Target Synonym: Midbrain nucleolar protein; midn; MIDN; Midnolin
Research Areas: Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q504T8
Background: Expression of themidnolingene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. Themidnolinencodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of themidnolinwas studied by usingmidnolin-green fluorescent protein (GFP) fusion proteins.Midnolinwas found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of themidnolin.May be involved in regulation of genes related to neurogenesis in the nucleolus
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human MIDN
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 49kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only