MIEN1 Polyclonal Antibody
Catalogue Numbers: BS60489-50, BS60489-100
Sizes: 50µl, 100µl
Alternative Name: Migration and invasion enhancer 1; HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35; MIEN1; C17orf37; RDX12; XTP4
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9BRT3
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: C35, also known as XTP4 (HBV X-transactivated gene 4) and protein C17orf37, is a 115 amino acid cytoplasmic protein that is a member of the SelWTH protein family. SelWTH proteins contain a thioredoxin-like fold and a conserved CxxC or CxxU motif, suggesting that they may play functional role in redox reactions. Although found at trace levels in normal breast ductal epithelium and testis, expression of C35 is robust in infiltrating ductal carcinomas of the breast, lobular carcinoma, as well as distant metastases of breast cancer such as liver, lung and skin. The prevalence and abundance of C35 overexpression in tumors suggest that it may be an appropriate bio-marker for diagnosis and a potential target for therapeutic intervention.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MIEN1 polyclonal antibody detects endogenous levels of MIEN1 protein.
Bioworld Molecular Weight: ~ 12 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of MIEN1 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human MIEN1.
Conjugate: Unconjugated
Modification: Unmodified