Product Description

Mimecan Polyclonal Antibody

Catalogue Numbers: BS67417-50, BS67417-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P20774

Host: Rabbit

Reactivity: Human, Bovine

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican,Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Mimecan protein.

Extra Notes: Western blot analysis of Mimecan expression in SKOVCAR3 (A), PC3 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Mimecan. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified