MKL1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12598-20, A12598-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 99kDa
Observed Molecular Weight: 145kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 57591
SWISS: Q969V6
Alternate Names: MAL; MKL; BSAC; MKL1; MRTF-A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Cytoskeleton, Endocrine Metabolism, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Heart, Cardiogenesis.
NCBI Alias: MRTFA
Research Use Only