ML-IAP Polyclonal Antibody - BT-AP05454

ML-IAP Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05454-20, BT-AP05454-50, BT-AP05454-100

Citations, Manuals and MSDS Available upon request.

Background: BIRC7 encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of baculoviral IAP repeat-containing protein 7 may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants.

Research Areas: Cell Biology

Target Protein: BIRC7

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ML-IAP Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 32798

UniProt Accession: Human: Q96CA5; Mouse: A2AWP0

Synonyms: BIRC7; KIAP; LIVIN; MLIAP; RNF50; Baculoviral IAP repeat-containing protein 7; Kidney inhibitor of apoptosis protein; KIAP; Livin; Melanoma inhibitor of apoptosis protein; ML-IAP; RING finger protein

GeneID: Human: 79444

Research Use Only