MLH1 Monoclonal Antibody-MB10336

MLH1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10336-50, MB10336-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P40692

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 85 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MLH1 in K562, C6, 3T3, Hela lysates using MLH1 antibody., Immunocytochemistry analysis of MLH1 in Hela using MLH1 antibody, and DAPI

Alternative Name: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Immunogen: A synthetic peptide of human MLH1

Conjugate: Unconjugated

Modification: Unmodified