Product Description

MLH1 Polyclonal Antibody

Sizes: 50 µl, 100 µl

Catalogue Numbers: BS6457-50, BS6457-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P40692

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB,1:500 - 1:2000 | IF,1:50 - 1:100

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Polyclonal Antibodies

Bioworld Molecular Weight: 85KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: MLH1; COCA2; FCC2; HNPCC; HNPCC2; hMLH1

Immunogen: A synthetic peptide of human MLH1(NP_000240.1).

Conjugate: Unconjugated

Modification: Unmodified