MLH1 Polyclonal Antibody - BT-AP05452

MLH1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05452-20, BT-AP05452-50, BT-AP05452-100

Citations, Manuals and MSDS Available upon request.

Background: MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MLH1

Applications: WB, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MLH1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 84601

UniProt Accession: Human: P40692; Mouse: Q9JK91; Rat: P97679

Synonyms: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

GeneID: Human: 4292; Mouse: 17350; Rat: 81685

Research Use Only