MLH1 rabbit pAb - ES2797

MLH1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2797-50, ES2797-100

Citations, Manuals and MSDS Available upon request.

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

Alternate Name: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 4292

Human SWISS Prot NO: P40692

Subcellular Location: Nucleus. Chromosome. Recruited to chromatin in a MCM9-dependent manner.

Research Use Only