MLK3 Monoclonal Antibody-MB11223

MLK3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11223-50, MB11223-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q16584

Host: Rabbit

Reactivity: Human

Applications: WB,ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MLK3 in HepG2, A431Lysates using MLK3 antibody.

Bioworld Molecular Weight: Calculated MW: 93 kDa; Observed MW: 93 kDa

Specificity: IgG

Alternative Name: MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase

Immunogen: A synthetic peptide of human MLK3

Conjugate: Unconjugated

Modification: Unmodified