Product Description

MLKL (5E3) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3294-50, MB3294-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q8NB16

Host: Mouse

Reactivity: Human

Applications: IHC-P

All Applications: IHC: 1/50-1/100

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: -

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using MLKL antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using MLKL antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: MLKL

Immunogen: Synthetic peptide conjugated to KLH.

Conjugate: Unconjugated

Modification: Unmodified