MLKL (8H7) Mouse mAb - EM1328

MLKL (8H7) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1328-50, EM1328-100

Citations, Manuals and MSDS Available upon request.

Background: Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.

Alternate Name: Mixed lineage kinase domain like protein, FLJ34389

Source: Mouse

Applications: IHC

Dilution: IHC 1:100-200

Reactivity: Human

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 54kDa

Human Gene ID: 197259

Human SWISS Prot NO: Q8NB16

Subcellular Location: Cell membrane,  Cytoplasm,  Membrane

Research Use Only