Product Description

MLKL Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11224-50, MB11224-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q8NB16

Host: Rabbit

Reactivity: Human

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MLKL in HT-29 lysates using MLKL antibody., Western blot analysis of MLKL in U251MG, Hela lysates using MLKL antibody.

Alternative Name: MLKL

Immunogen: Recombinant protein of human MLKL

Conjugate: Unconjugated

Modification: Unmodified