Product Description

MLL2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11381-20, BT-AP11381-50, BT-AP11381-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Research Areas: Epigenetics and nuclear signaling

Target Protein: MLL2

Applications: IHC-p, IF

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Histone-lysine N-methyltransferase MLL2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O14686; Mouse: Q6PDK2

Synonyms: Histone-lysine N-methyltransferase MLL2;EC 2.1.1.43;ALL1-related protein;Lysine N-methyltransferase 2D;KMT2D;Myeloid/lymphoid or mixed-lineage leukemia protein 2

GeneID: Human: 8085

Research Use Only