MLTK Polyclonal Antibody - BT-AP05467

MLTK Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05467-20, BT-AP05467-50, BT-AP05467-100

Citations, Manuals and MSDS Available upon request.

Background: MLTK is a member of the MAPKKK family of signal transduction molecules and encodes a protein, Mitogen-activated protein kinase kinase kinase MLT, with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Areas: Signal Transduction

Target Protein: MLTK

Applications: WB, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MLTK Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 91181

UniProt Accession: Human: Q9NYL2; Mouse: Q9ESL4

Synonyms: MLTK; ZAK; HCCS4; Mitogen-activated protein kinase kinase kinase MLT; Human cervical cancer suppressor gene 4 protein; HCCS-4; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitog

GeneID: Human: 51776; Mouse: 65964

Research Use Only