MMP-1 Monoclonal Antibody - RA10629

MMP-1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA10629-50, RA10629-100

Citations, Manuals and MSDS Available upon request.

Background: matrix metallopeptidase 1 (MMP1) Homo sapiens This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD) . Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; FCM; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 4312

SWISS: P03956

Source: Mouse

Research Use Only