MMP-17 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90869-50, BS90869-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9ULZ9(Human) Q9R0S3(Mouse)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: ICC IF, IHC WB,
All Applications: ICC:1:50
IHC:1:50
WB:1:500
Background: Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: MMP-17 polyclonal antibody detects endogenous levels of MMP-17 protein.
Bioworld Molecular Weight: 67 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: MMP-17, MT-MMP 4, MTMMP4, MT4-MMP, MT4MMP, MMP17, MT4MMP, Matrix metalloproteinase 17, Matrix metalloproteinase 17 membrane inserted, Matrix metalloproteinase-17, Membrane type 4 matrix metalloproteinase, Membrane type matrix metalloproteinase 4, Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase, MMP 17, MMP-17, Mmp17, MMP17, MT MMP 4, MT MMP4, MT-MMP 4, MT4 MMP, MT4-MMP, MT4MMP, MTMMP 4, MTMMP4,
Immunogen: Recombinant protein within human MMP17 aa 1-250.
Conjugate: Unconjugated
Modification: Unmodified