Product Description

MMP-2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90871-50, BS90871-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P08253(Human) P33434(Mouse) P33436(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200

Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP2 antibody. Counter stained with hematoxylin.

Bioworld Molecular Weight: 72 kDa

Specificity: MMP-2 polyclonal antibody detects endogenous levels of MMP-2 protein.

Alternative Name: MMP-2, 72 kDa gelatinase, 72kD type IV collagenase, CLG 4, CLG 4A, CLG4, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase, Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), Matrix Metalloproteinase 2, Matrix metalloproteinase II, Matrix metalloproteinase-2, MMP 2, MMP II, MMP-2, MMP2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE 1, TBE-1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified