MMP-8 rabbit pAb - ES6260

MMP-8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6260-50, ES6260-100

Citations, Manuals and MSDS Available upon request.

Background: matrix metallopeptidase 8 (MMP8) Homo sapiens This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Alternate Name: MMP8; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-8. AA range:418-467

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 4317

Human SWISS Prot NO: P22894

Subcellular Location: Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Stored in intracellular granules.

Research Use Only