Product Description

MMP2 (3A8) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3046-50, MB3046-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P08253

Host: Mouse

Reactivity: Human, Mouse

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 74 kDa; Observed MW: 74 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MMP2 in CHO-K1 and CHO-K1 transfected by MMP2 fragment lysates using MMP2 antibody., Immunofluorescence analysis of MMP2 in Hela using MMP2 antibody, and DAPI., Western blot analysis of MMP2 in Raw264.7 lysates using MMP2 antibody.

Alternative Name: MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1

Immunogen: Purified recombinant human MMP-2 protein expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified